Abstract Background Gout is a prevalent manifestation of metabolic osteoarthritis induced by elevated blood uric acid levels.The purpose of this study was to investigate the mechanisms of gene expression regulation in gout disease and elucidate its pathogenesis.Methods The study integrated gout genome-wide association study (GWAS) data, single-cell

The evolution of climate and of electrical devices are raising users’ awareness about the protection of structures and plants against common overvoltage phenomena and those ones of atmospheric origin.Therefore, a continuous evolution of thunderstorm phenomena, increasingly concentrated and intense, is occurring.Conversely, electric devices ar

Fraxinus species belongs to the Oleaceae family, commonly known as Ash tree, and has been utilized as a folk medicine with various medicinal properties, including anti-obesity activity.The goal of the present study was to establish quality control parameters using microscopic characterization, phytochemical differentiation, and anti-lipase activity

IntroductionBipolar disorder is characterized by severe mood symptoms including major depressive and manic episodes.During manic episodes, many patients show cognitive dysfunction.Dopamine and glutamate are important for cognitive processing, thus the COMT and DAOA genes that modulate the expression of these neurotransmitters are of interest for st

Wetlands are globally recognized as ecosystems that provide livelihood opportunities in aptly structured management contexts.Many wetlands, particularly those in urban Uganda are, however, getting degraded through Side Chair infilling, construction, extraction, agricultural and industrial production despite the existing resource management regime.T